What are OneChoice recommendations based on?

OneChoice starts with published clinical evidence and the patient and laboratory information sent to Arkstone.

What sources does OneChoice use?

Sources may include clinical guidelines from organizations such as the Infectious Diseases Society of America (IDSA), public-health guidance from agencies such as the CDC, FDA-approved prescribing information, and peer-reviewed research.

Guidelines bring together findings from many studies, while primary research can help answer questions that a guideline or drug label does not fully cover. This is especially useful for less common organisms, resistance mechanisms, specimen sources, or treatment scenarios.

What happens when the evidence is limited?

OneChoice does not pretend there is certainty when the literature is unclear. It may mark a drug as having unclear efficacy, leave a dose or duration undefined, choose a more conservative option, or indicate that treatment may not be needed.

The references behind a recommendation are available in OneChoice Plus through the QR code on the report. They help explain the recommendation, but they do not replace review of the complete patient record or the clinician's judgment.