How is antibiotic dosing determined?

Modified on Wed, Sep 2 at 11:34 AM

OneChoice provides an evidence-based dose and route as a starting point for the drug, diagnosis, specimen source, and patient information shown on the report.

Dosing information may come from FDA-approved prescribing information, clinical guidelines, and peer-reviewed literature.

Will the displayed dose fit every patient?

Not always. The right dose can depend on age, weight, renal and hepatic function, dialysis, infection severity and site, pregnancy or breastfeeding, drug interactions, oral absorption, and whether therapeutic drug monitoring is needed.

How can OneChoice Plus help?

OneChoice Plus includes tools for estimating creatinine clearance (CrCl) and eGFR, along with drug-specific renal and hepatic considerations. LiveFactor lets you enter renal or hepatic information while reviewing the report.

These tools make patient-specific review easier, but they do not replace pharmacy review, therapeutic drug monitoring, or institutional protocols. Confirm the dose against the patient's current organ function, medication list, and complete clinical record before prescribing.

If the evidence does not support a reliable dose for the scenario, OneChoice may show the dose as undefined rather than suggest certainty that is not supported. See Why would a report show an undefined dose or duration?

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