Does OneChoice factor in what was not detected or not tested for?

No. 

By the very nature of microbial life, in any given lab test there are going to be any number of organisms or genes that are not tested for. Basing a treatment plan on what wasn't tested or detected by the lab can be an impossible task, since, according to some literature, there are about a trillion species of microorganisms as well as thousands of resistance genes. many of which are unaccounted for. Best practices for antimicrobial stewardship encourage the use of diagnostic tests to confirm the presence of infection prior to treating, and avoid treatment based on best guesses or unknowns which often lead to prescribing antibiotics when medically unnecessary.

The OneChoice report uses data that is detected by the laboratory to make the best possible recommendation based on the data available but cannot take into consideration what was not detected or tested for. This includes resistance genes or organisms that may be present, but not tested for, in addition to sensitivity data or culture data not tested for or sent to Arkstone.

There are many different types of molecular tests, resistance genes, and cultures (AFB cultures, fungal cultures and bacterial cultures to name a few) and depending on which test or combination of tests are used, can impact the positive or negative predictive value as well as the recommendation itself.